Back مستقبلات الهستامين Arabic Histamin-Rezeptoren German Histamine receptor English Receptor de histamina Spanish گیرنده هیستامین Persian Reseptor histamin ID Recettore dell'istamina Italian ヒスタミン受容体 Japanese Receptory histaminowe Polish Receptor de histamina Portuguese
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Receptoria histamini sunt receptoria neurotransmissoria et classis receptoriorum proteino G copulatorum cum histamino ligando endogeno[1].
Adhuc quattuor typi receptoriorum histamini noti sunt[2]:
- Receptorium histamini H1 - Contractiones ilei, vasodilatatio, pruritus, bronchoconstrictio. Antagonista H1 receptorii: Diphenhydraminum, Loratadinum, Cetirizinum, Fexofenadinum, Clemastinum
- Receptorium histamini H2 - Stomachus: incrementum secretionis chymi. Antagonista H2 receptorii: Ranitidinum, Cimetidinum, Famotidinum, Nizatidinum
- Receptorium histamini H3 - deminutio concentrationis in cerebro Acetylcholini, Serotonini, Noradrenalini
- Receptorium histamini H4 - Chemotaxis (mastocytus)
- ↑ Classificatio internationalis receptorum Histamini: Hill SJ, Ganellin CR, Timmerman H, Schwartz JC, Shankley NP, Young JM, Schunack W, Levi R, Haas HL (1997). Pharmacol. Rev. 49 (3): 253–78
- ↑ Panula P., Chazot P. L., Cowart M., Gutzmer R., Leurs R., Liu W. L., Stark H., Thurmond R. L., Haas H. L. (2015). "International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors". Pharmacological reviews 67 (3): 601-55.