Receptorium histamini H3

Receptorium histamini H3
Alia HRH3, GPCR97
Fontes
ext.
OMIM: 604525
Locus geni (homo)
Chromosomate 20 locatum
Chr. Chromosoma 20 (humanum)

Receptorium histamini H3 (abbreviatura:; H3R) est receptorium histamini praesynapticum et familiae receptoriorum proteino G copulatorum. Receptoria imprimis in systemate nervosi centrali inveniuntur atque in systemate peripherico velut in intestinis.

An anno 1990 duos subtypos receptorii investigatum esse putatum est[1].

Antagonista receptorii histamini H3 tempore futuro therapiis contra epilepsias vel morbos neurodegenerativos levare possint[2].

  1. West R. E. Jr., Zweig A., Shih N. Y., Siegel M. I., Egan R. W., Clark M. A. (1990). "Identification of two H3-histamine receptor subtypes". Molecular pharmacology 38 (5): 610-3 
  2. Bhowmik M., Khanam R., Vohora D. (2012). "Histamine H3 receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives". British journal of pharmacology 167 (7): 1398-414 

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