5-HT1E receptor

5-HT1E serotoninski receptor
Identifikatori
Simboli	HTR1E; 5-HT1E
Vanjski ID	OMIM: 182132 HomoloGene: 55491 IUPHAR: 5-ht1e GeneCards: HTR1E Gene
Ontologija gena Molekularna funkcija • aktivnost rodopsinu-sličnog receptora • receptorska aktivnost • aktivnost serotoninskog receptora Celularna komponenta • integralno sa ćelijskom membranom • membrana Biološki proces • prenos signala • G-proteinska signalizacija, spregnuta sa cikličnim nukleotidnim sekundarnim glasnikom • sinaptička transmisija
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta	Čovek	Miš
Entrez	3354	n/a
Ensembl	ENSG00000168830	n/a
UniProt	P28566	n/a
RefSeq (mRNA)	NM_000865	n/a
RefSeq (protein)	NP_000856	n/a
Lokacija (UCSC)	Chr 6: 87.7 - 87.78 Mb	n/a
PubMed pretraga	[1]	n/a

5-HT1E receptor, (5-hidroksitriptaminski (serotoninski) 1E receptor, 5-HT_1E) je visoko izraženi humani G-protein spregnuti receptor^[1] koji pripada familiji 5-HT1 receptora (G_i-spregnutih serotoninskih receptora).^[2][3] Humani gen se označava sa HTR1E.^[4]

1. ↑ Leonhardt S., Herrick-Davis K. and Titeler M. (1989) Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein. Journal of neurochemistry 53, 465-471. (1989). „Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein.”. Journal of neurochemistry 53 (2): 465–71. DOI:10.1111/j.1471-4159.1989.tb07357.x. PMID 2664084. 
2. ↑ McAllister G., Charlesworth A., Snodin C., Beer M. S., Noble A. J., Middlemiss D. N., Iversen L. L. and Whiting P. (1992) Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype. Proceedings of the National Academy of Sciences of the United States of America 89, 5517-5521. (1992). „Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.”. Proceedings of the National Academy of Sciences of the United States of America 89 (12): 5517–21. DOI:10.1073/pnas.89.12.5517. PMC 49323. PMID 1608964. 
3. ↑ Levy F. O., Gudermann T., Birnbaumer M., Kaumann A. J. and Birnbaumer L. (1992) Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase. FEBS Lett 296, 201-206. (1994). „Assignment of the gene encoding the 5-HT1E serotonin receptor (S31) (locus HTR1E) to human chromosome 6q14-q15.”. Genomics 22 (3): 637–40. DOI:10.1006/geno.1994.1439. PMID 8001977. 
4. ↑ „Entrez Gene: HTR1E 5-hydroxytryptamine (serotonin) receptor 1E”.