Dapiprazol

Dapiprazol

(IUPAC) ime
32-[4-(2-metilfenil)piperazin-1-il]etil5,6,7,8- tetrahidro-[1,2,4]triazolo[4,5-a]piridin
Klinički podaci
AHFS/Drugs.com	Potrošačka informacije o leku
MedlinePlus	a601043
Identifikatori
CAS broj	72822-12-9
ATC kod	S01EX02
PubChem[1][2]	3033538
DrugBank	DB00298
ChemSpider[3]	2298190
UNII	5RNZ8GJO7K Y
KEGG[4]	D07775 Y
ChEBI	CHEBI:51066 Y
ChEMBL[5]	CHEMBL1201216 Y
Hemijski podaci
Formula	C19H27N5
Mol. masa	325,451 g/mol
SMILES	eMolekuli & PubHem
InChI InChI=1S/C19H27N5/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19/h2-3,6-7H,4-5,8-15H2,1H3 Y Key: RFWZESUMWJKKRN-UHFFFAOYSA-N Y
Farmakokinetički podaci
Bioraspoloživost	Zanemarljiva pri topičkom doziranju
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	℞ Prescription only
Način primene	Topikalno (kapi za oči)

Dapiprazol (Rev-Eyes) je alfa blokator. On se koristi za oporavak od midrijaze nakon pregleda očiju.^[6]

1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
4. ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
5. ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
6. ↑ Doughty, Michael J.; Lyle, William M. (May 1992). „A Review of the Clinical Pharmacokinetics of Pilocarpine, Moxisylyte (Thymoxamine), and Dapiprazole in the Reversal of Diagnostic Pupillary Dilation”. Optometry & Vision Science 69 (5).