Tiramin

Tiramin
IUPAC ime	4-(2-aminoetil)fenol
Identifikacija
CAS registarski broj	51-67-2 Y
PubChem[1][2]	5610
ChemSpider[3]	5408 Y
UNII	X8ZC7V0OX3 Y
KEGG[4]	C00483
MeSH	Tyramine
ChEBI	15760
ChEMBL[5]	CHEMBL11608 Y
Jmol-3D slike	Slika 1
SMILES Oc1ccc(cc1)CCN
InChI InChI=1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2 Y Kod: DZGWFCGJZKJUFP-UHFFFAOYSA-N Y InChI=1/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2 Kod: DZGWFCGJZKJUFP-UHFFFAOYAB
Svojstva
Molekulska formula	C8H11NO
Molarna masa	137,179 g/mol[6]
Agregatno stanje	Bezbojna tečnost
Gustina	1,20 g/cm3[7]
Tačka topljenja	164-165 °C [8]
Tačka ključanja	205-207 °C na 25 mm Hg; 166 °C na 2 mm Hg [8]
Rastvorljivost u vodi	1 g in 95 mL na 15 °C [8]
pKa	9,74 (OH); 10,52 (NH3+) [9]
Y (šta je ovo?)   (verifikuj) Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
Infobox references

Tiramin (4-hidroksifenetilamin, para-tiramin, midrijal, uteramin) je prirodni monoamin jedinjenje i trag amin izveden iz aminokiseline tirozina.^[6] Tiramin deluje kao kateholamin [ dopamin, norepinefrin (noradrenalin), epinefrin (adrenalin)] otpuštajući agenst. On nema sposobnost prolaska kroz krvno moždanu barijeru, te ispoljava jedino periferne simpatomimetičke efekte.

1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
4. ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
5. ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
6. ↑ ^{6,0 6,1} PubChem
7. ↑ A. M. Andersen (1977). "The crystal and molecular structure of tyramine hydrochloride." Acta Chem. Scandinavica B 31 162-166.
8. ↑ ^{8,0 8,1 8,2} The Merck Index, 10th Ed. (1983), p.1405, Rahway: Merck & Co.
9. ↑ Kappe, T. (1965). „Ultraviolet Absorption Spectra and Apparent Acidic Dissociation Constants of Some Phenolic Amines”. Journal of Medicinal Chemistry 8: 368-374.