In cell biology, the centrosome is an organelle that is the main place where cell microtubules are organized. Also, it regulates the cell division cycle, the stages which lead up to one cell dividing in two.
The centrosome has apparently only evolved in animal cells.[3]Fungi and plants use other structures to organize their microtubules.[4] Although the centrosome has a key role in efficient mitosis in animal cells, it is not necessary.[5]
A centrosome is composed of two centrioles at right angles to each another. They are surrounded by a shapeless mass of protein.
↑Wunderlich V. 2002. JMM - past and present. Journal of Molecular Medicine80 (9): 545–548. doi:10.1007/s00109-002-0374-y. PMID 12226736.
↑Bornens M.; Azimzadeh J. 2007. Origin and Evolution of the Centrosome. Advances in experimental medicine and biology607: 119–129. doi:10.1007/978-0-387-74021-8_10. PMID 17977464.
↑Schmit 2002. Acentrosomal microtubule nucleation in higher plants. International Review of Cytology220: 257–89. doi:10.1016/S0074-7696(02)20008-X. PMID 12224551.
↑Mahoney N.M.; Goshima G.; Douglass A.D.; Vale R.D. 2006. Making microtubules and mitotic spindles in cells without functional centrosomes. Current Biology16 (6): 564–569. doi:10.1016/j.cub.2006.01.053. PMID 16546079.