Spartanburg is a city in and the seat of Spartanburg County, South Carolina, United States.[1] It is the 11th-largest city by population in the state. The city of Spartanburg has a population of 38,732 as of the 2020 census.[2] The Spartanburg Metropolitan Statistical Area, including Spartanburg and Union counties, had a population of 355,241 as of the 2020 census.