Vino Nobile di Montepulciano (in English lit. Noble Wine of Montepulciano) is a red wine with Denominazione di Origine Controllata e Garantita status produced in the vineyards in the town of Montepulciano, Tuscany, Italy. The wine is made for the main part from the Sangiovese grape varietal (minimum 70%), blended with Canaiolo Nero (10%–20%) and small add of other local varieties such as Mammolo. The wine is aged in oak barrels for 2 years; three years if it is a riserva. The wine should not be confused with Montepulciano d'Abruzzo, a red wine made from the Montepulciano grape in the Abruzzo region of east-central Italy.