HLA-C

Major histocompatibility complex, class I, C
主要组织相容性抗原复合物，第一类，C
Major histocompatibility complex, class I, C; 主要组织相容性抗原复合物，第一类，C
	Illustration of an HLA-C showing the HLA-B 'alpha' chain, ?2-Microglobulin, and the end of a peptide bound in the binding cleft.
有效结构
PDB	直系同源检索：PDBe, RCSB
PDB查询代码列表
	3BZF
标识
代号	HLA-C; D6S204; HLA-JY3; HLC-C; PSORS1
扩展标识	遗传学：142840 同源基因：133080 GeneCards: HLA-C Gene
基因本体论描述
分子功能	· MHC class I receptor activity;
细胞成分	· Golgi membrane; · extracellular region; · plasma membrane; · integral to plasma membrane; · ER to Golgi transport vesicle membrane; · phagocytic vesicle membrane; · early endosome membrane; · MHC class I protein complex; · integral to lumenal side of endoplasmic reticulum membrane;
生物过程	· antigen processing and presentation of peptide antigen via MHC class I; · antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; · antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; · immune response; · virus-host interaction; · cytokine-mediated signaling pathway; · antigen processing and presentation of exogenous peptide antigen via MHC class I; · innate immune response; · regulation of immune response; · interferon-gamma-mediated signaling pathway; · type I interferon-mediated signaling pathway;
	Sources: Amigo / QuickGO
RNA表达模式
	更多表达数据
直系同源体
物种	人类
Entrez	3107
Ensembl	ENSG00000204525
UniProt	P10321
mRNA序列	NM_001243042
蛋白序列	NP_001229971
基因位置	Chr 6:; 31.24 – 31.24 Mb
PubMed查询	[1]
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HLA-C是人類白細胞抗原（HLA）的一个基因座，位于6号染色体上。成熟的HLA-C蛋白会与β2微球蛋白组成异二聚体，作为一个受体锚定在细胞表面。

HLA-C

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