The 1944 United States Senate special election in Massachusetts was held on November 7, 1944. Republican Governor Leverett Saltonstall was elected to finish the term of Henry Cabot Lodge Jr., who had resigned from the Senate to serve in World War II.
Primary elections were held on July 10; Saltonstall was unopposed for the Republican nomination, while John H. Corcoran won a highly competitive race for the Democratic nomination, in which all four candidates came from Boston or Cambridge.