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Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available.[1]: 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise. Clinical management varies widely, with many patients receiving combinations of therapies.[2] The prognosis of ME/CFS is poor, with recovery considered “rare”.[3][4]
There are no Food and Drug Administration-approved medications for ME/CFS, although medications are sometimes used without approval for the illness (off-label). Drugs have been used in experimental studies of the illness that have not been approved for market for any condition in the United States (for example, isoprinosine and rintatolimod).[5] Rintatolimod has been approved for import and use in Argentina.[6][7]
- ^ "Recommendations – Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management – Guidance". National Institute for Health and Care Excellence (NICE). 29 October 2021. Archived from the original on 8 February 2024. Retrieved 9 March 2024.
- ^ Chou R, McDonagh M, Griffins J, Grusing S (2022). Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): An Updated Systematic Evidence Review (PDF). Centers for Disease Control and Prevention. Archived (PDF) from the original on 14 February 2024. Retrieved 30 March 2023.
- ^ Luyten P, Van Houdenhove B, Pae CU, Kempke S, Van Wambeke P (December 2008). "Treatment of chronic fatigue syndrome: findings, principles and strategies". Psychiatry Investigation. 5 (4): 209–12. doi:10.4306/pi.2008.5.4.209. PMC 2796012. PMID 20046339.
- ^ Van Cauwenbergh D, De Kooning M, Ickmans K, Nijs J (October 2012). "How to exercise people with chronic fatigue syndrome: evidence-based practice guidelines". European Journal of Clinical Investigation. 42 (10): 1136–44. doi:10.1111/j.1365-2362.2012.02701.x. PMID 22725992. S2CID 24546500.
- ^ Smith ME, Haney E, McDonagh M, Pappas M, Daeges M, Wasson N, et al. (June 2015). "Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop". Annals of Internal Medicine. 162 (12): 841–50. doi:10.7326/M15-0114. PMID 26075755. S2CID 28576363.
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