Wyoming Central Railway was a railroad in the U.S. state of Wyoming. The railroad was incorporated in October 1885 and built a line from Chadron, Nebraska through Douglas to Casper. The line was initially leased to the Fremont, Elkhorn and Missouri Valley Railroad and the two railroads consolidated in 1891. The FE&MV was merged into Chicago and North Western Transportation Company in 1903 and the line was extended to Lander.